A study published in The Journal of Clinical Investigation states that obesity doesn’t go hand in hand with metabolic problems that cause diabetes, heart disease and stroke.
The research showed that obese people with normal metabolic profile do not develop these diseases even after gaining additional weight. Key measurements were identified that distinguished metabolically normal obese study participants from those with problems.
One of them was presence of fat in the liver while the other difference was the gene function in fat tissue. People with normal metabolism in spite of their obesity expressed more genes that regulate fat production and accumulation.
The study involved 20 obese participants who were asked to gain about 15 pounds over several months. After they gained weight, the metabolic profiles of the participants remained normal if they were in the normal range when the study began but the metabolic profiles worsened in participants whose metabolic profiles were abnormal when the study got underway.